Breathing exercises, meditation improved inflammatory markers, quality of life in IBD patients

Breathing exercises, meditation improved inflammatory markers, quality of life in IBD patients


SAN DIEGO — Patients with mild-to-moderate inflammatory bowel disease who participated in a program of breathing, movement and meditation exercises experienced significant improvement to inflammatory markers and quality of life in a study presented at the American College of Gastroenterology Annual Scientific Meeting.

Researchers randomized 30 patients with mild-to-moderate IBD to participate in either a breathing, movement and meditation workshop (BBMW) or a control group undergoing a parallel educational seminar (ES). Inflammatory and psychometric markers were assessed via brief symptom inventory (BSI), Beck anxiety inventory (BAI), Beck depression index and IBD questionnaire (IBDQ) at baseline, with changes after 6 weeks as the primary endpoint and after 6 months as the secondary endpoint. Both groups received similar access to health care professionals.

Patients in the BBMW group experienced significant improvements to BSI after 6 weeks compared with the ES group (P=.02 for difference). Similarly, quality of life as measured by the IBDQ (P=.01) was significantly improved in the BBMW group, as were symptoms of anxiety (P=.02). These improvements all persisted after 6 months (P=.04 for BSI score, P=.03 for BSAI and P=.01 for IBDQ), and investigators noted additional improvements to perceived stress (P=.01), perceived disability (P=.001) and depression (P=.01).

At 6 weeks, fecal calprotectin levels had improved significantly in the ES group (P=.04), and numerically in the BBMW group. These changes were not maintained at the 6-month evaluation.

“Many of our young patients with IBD have a decreased quality of life from many symptoms, including diarrhea, bleeding and abdominal pain,” researcher Vinita E. Jacob, MD, assistant clinical professor of medicine at New York Presbyterian Hospital, Weill Cornell Medical College, “… While we have excellent medical therapy, it’s important to be broad-minded about other techniques that can be helpful in decreasing the inflammatory state in these particular patients. There are so many young patients who do not want to be on lifelong medication therapy; there is a role for stimulating the parasympathetic nervous system in these patients to help them feel better.”

Disclosure: The researchers report no relevant financial disclosures.

For more information:

Jacob VE. P1064: Impact of Breathing and Education Programs on Inflammatory Bowel Disease (IBD) Quality of Life (QOL) and Inflammatory Biomarkers. Presented at: The American College of Gastroenterology Annual Scientific Meeting; Oct. 11-16, San Diego.

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